Wednesday 13 August 2008

Piggy-backing Vaccine

The Medical Research Council have discovered a new way of providing a malaria vaccine which utilises cold and pox viruses. As the report explains:
"The new method has proved completely protective in mice and has been shown to reduce the growth of human malaria in laboratory tests by between 70 and 85 percent, depending on the strain. It involves using two viruses, an optimised adenovirus (the common cold) and 8 weeks later the pox virus (used to eradicate smallpox and in many vaccines since), both of which are genetically engineered to express a malaria protein."
The original research paper: Effective induction of high-titer antibodies by viral vector vaccines by SJ Draper et al is published in the journal Nature Medicine, and can be read online here.

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